DFG extends CRC funding to university and university medical center G


PICTURE: Dynamic changes in materials during energy conversion. Above, the dynamic structure of the interface between water and the electrode during electrolysis (Lole et al, Nature Communication Materials 2020), below an ultra-fast view … After

Credit: University of Göttingen

The German Research Foundation (DFG) has extended its funding for two Collaborative Research Centers in Göttingen (CRC) from July 1, 2021. This means that the CRC 1073 “Atomic-scale control of energy conversion “of the Faculty of Physics of the University of Göttingen will enter its third successful funding period. The CRC started in October 2013, coordinated by Professor Christian Jooß from the Institute for Material Physics. CRC 1286 “Quantitative Synaptology” at the University Medical Center Göttingen (UMG) has obtained support for a second funding period. The head of research is Prof. Silvio Rizzoli, director of the Institute of Sensory Neurophysiology and head of research at the Center for Biostructural Imaging of Neurodegeneration (BIN) at UMG. Funding amounts to around ten million euros per year over four years.

CRC 1073 Atomic scale control of energy conversion

The CRC Atomic Scale Control of Energy Conversion is based at the Faculty of Physics and Faculty of Chemistry of the University of Göttingen, as well as the Max Planck Institute for Biophysical Chemistry (MPIBPC) in Göttingen. In addition, a research group from the Clausthal University of Technology, the German Electron Synchrotron (DESY) in Hamburg and the Helmholtz-Zentrums für Materialien und Energie in Berlin are involved.

New materials that allow better control of energy conversion are of great importance for advanced applications in solar cells and electrochemical energy storage. Over the past few years, CRC has achieved a series of breakthroughs in the fundamental understanding of the elementary stages of energy conversion in these fields. At the heart of this is the understanding that materials can exist in a state markedly different from their standard equilibrium state due to “correlated excitations”. This refers to the stimulation of particles in a material – in the same way you might light up electrons in a solar cell – affecting their behavior to create a new state of the material where the particles interact strongly. This new state makes it possible to control, convert and exploit energy for a number of applications. In our example, the “hot” electrons excited in a solar cell can be stabilized with the potential to increase their efficiency far beyond that of conventional systems.

The innovative, high-resolution and ultra-fast experimental methods developed by CRC researchers are of particular importance for this research theme. “The application of these unique methods to our model systems has been a crucial contribution to the remarkable knowledge about energy conversion processes,” said Jooß. In the third funding period, which begins now, scientists want to develop a new strategy to control energy conversion in materials through globally correlated excitations and find out how this can be transferred to applications.

Further information can be found at https: //www.uni-goettingen.of/Fr/437142.html

CRC 1286 Quantitative Synaptology

The goal of CRC 1286 Quantitative Synaptology is to describe presynaptic and postsynaptic processes so precisely that a computer-assisted simulation of a functioning virtual synapse is made possible. In the future, computer-assisted simulation of synapses could help better understand neurological and neurodegenerative diseases and, potentially, their healing mechanisms.

In the first phase of funding, scientists at CRC 1286 collected as much structural and functional data as possible for an “ideal” synapse model. To this end, they investigated the molecular composition of synapses during their resting and active phases, the exact positions of synaptic organelles and proteins as well as their number, post-translational changes and interactions. In the second phase of funding, these data can now be refined through further experimental work in the laboratory. At the same time, new projects in the field of computational neuroscience complement the CRC, which strongly strengthens the computational aspects. These now address several questions about synaptic transmission, from protein movement and organization at the nanoscale to long-term dynamics and plasticity. “The results of these projects will optimally position us to establish models of synaptic function during the third funding period,” said Rizzoli. “In the third funding period, our work will then reach its peak. In this final phase, we then want to focus on computer modeling, ”explains Rizzoli.

Scientists from 27 research groups in fields as diverse as neuroscience, physics, chemistry and medical statistics on the Göttingen campus work together in 26 individual projects. Researchers from eight UMG institutes and clinics, four University institutes, the Max Planck Institutes for Biophysical Chemistry, Experimental Medicine and Dynamics and Self-organization as well as the German Center for Neurodegenerative Diseases (DZNE – site de Göttingen), are involved. Also involved: the Institute for Biology of Medical Systems at the University Medical Center Hamburg-Eppendorf (UKE), the Max Planck Institute for Medical Research (MPI MF) in Heidelberg, the German Center for Neurodegenerative Diseases (DZNE-B – Berlin site) and the Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin.

Further information can be found at https: //www.sfb1286.of/? lang =Fr

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Contact:

Professor Christian Jooß

University of Göttingen

Faculty of Physics – Institute of Materials Physics

Friedrich-Hund-Platz 1, 37077 Göttingen, Germany

Phone: +49 (0) 551 39-5303

Email: [email protected]

Professor Silvio Rizzoli

Göttingen University Medical Center (UMG)

Institute of Neuro- and Sensory Physiology

Humboldtallee 23, 37073 Göttingen, Germany

Phone: +49 (0) 551 39-5912

Email: [email protected]

http: // www.neuro-physiol.med.uni-goettingen.of/wordpress /

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