American society – Vet Clin Path Journal http://vetclinpathjournal.org/ Sun, 09 Jan 2022 11:21:06 +0000 en-US hourly 1 https://wordpress.org/?v=5.8 https://vetclinpathjournal.org/wp-content/uploads/2021/05/cropped-icon-32x32.png American society – Vet Clin Path Journal http://vetclinpathjournal.org/ 32 32 Op-Ed: The Right-Wing Mindset of Today’s Conspiracy Theory Goes Back to the John Birch Society https://vetclinpathjournal.org/op-ed-the-right-wing-mindset-of-todays-conspiracy-theory-goes-back-to-the-john-birch-society/ Sun, 09 Jan 2022 11:00:12 +0000 https://vetclinpathjournal.org/op-ed-the-right-wing-mindset-of-todays-conspiracy-theory-goes-back-to-the-john-birch-society/

If you are looking for the roots of the current bizarre conspiracy and anger-driven politics, you have to look beyond Donald Trump’s presidency or even the rise of social media or talk radio – back to accusers, arsonists, rhetoric far-fetched John Birch Society in the 1960s and 1970s.

It’s starting to fade into history, but the John Birch Society was once the most formidable anti-Communist organization of the Cold War era. Named after a U.S. Army captain killed by Chinese Communists, it was founded in 1958 by North Carolina-born candy tycoon Robert Welch. (His company created the caramel “Sugar Daddy” on a stick.) Most Americans heard of the company after March 20, 1961, when it was widely reported that Welch called former President Eisenhower a communist. .

It was an outrageous and ridiculous claim, but Welch was just beginning to weave his paranoia tapestry. He saw Communist plots hiding in middle schools, high schools and the government.

Fluoride was used to piss off Americans before the coming Communist occupation, he said.

Welch also called the civil rights movement a communist conspiracy.

Welch’s plots fueled postwar America’s growing distrust of government and its belief in top cover-ups. He had a particular influence in California, which played an inordinate role in the growth of the John Birch Society.

With epicenters in Orange County and Los Angeles, the California Birchers helped secure the loss of governor Richard Nixon in 1962, the Republican presidential nomination of Barry Goldwater in 1964, and victory in office. from Governor Ronald Reagan in 1966. Several members of Congress in California were Birchers, including Representatives Edgar Hiestand and John Rousselot, both of whom represented parts of Los Angeles County.

Over the years, Welch’s theories have grown wilder. He eventually concluded that communism was just another name for the conspiracy started by the Bavarian Illuminati in 1776. He also said that the Trilateral Commission, the Council on Foreign Relations and the Bilderbergers (a group that sought to fostering dialogue between Europe and North America) were the puppeteers of the foreign and economic interests of the United States. The company also called on the United States to withdraw from the United Nations and remove Chief Justice Earl Warren from office.

In the 1970s, the John Birch Society became even more influential. Despite a widespread belief that William F. Buckley’s “responsible” right wing had purged the Conservative Bircher movement, Welch was never excommunicated. His style of American conservatism has remained strong.

During these years Welch broadened the reach of society by opposing abortion, high taxes, and sex education – issues that propelled the Reagan Revolution. Bircher Lewis Uhler was instrumental in passing Proposition 13 to lower California property taxes in 1978.

All the while, Welch continued to argue his extreme theories.

In the 1970s, Americans began to receive confirmation that conspiracies might not be as rare and crazy as they seemed. In 1973 and 1974, Watergate demonstrated that a president could secretly abuse his constitutional authority. The Americans learned that more government officials had spied for the Soviet Union and worked with mobsters in a futile effort to kill a foreign head of state. The CIA was found to have carried out LSD experiments on Americans. After a while, everything seemed plausible. In the years that followed, the number of people who said they trusted the government plummeted.

Welch matters today because from the 1980s and beyond his world became ours. The depth of his influence in transforming the Republican Party – and therefore America – has never been fully appreciated. His political style remained extremely powerful after his death in 1985.

Reagan espoused conspiracy theories, such as his claim that Gerald Ford organized assassination attempts against himself to gain sympathy votes. In the 1990s, partisanship became more central, ideology more crucial. On the radical fringes of the far right, private militiamen have armed themselves to the teeth. Both major parties, they said, wanted to end US sovereignty. After the sieges of Ruby Ridge and Waco in 1992 and 1993, the militia movement became even more conspiratorial.

It wasn’t until a few years later, in 1996, that Alex Jones launched his conspiratorial radio show “The Final Edition”. Jones claimed the government planned the Oklahoma City bombings in 1995 and plotted to assassinate Branch Davidians in Waco. Rush Limbaugh’s attacks on Bill and Hillary Clinton were in the same vein. Hillary covered up the murder of Vince Foster, suggested Limbaugh.

On the afternoon of September 11, 2001, Jones declared that “every act of terrorism that we have reviewed, from the World Trade Center, from Oklahoma City to Waco, was government action.” In 2006, at least a third of Americans believed their government planned or allowed the 9/11 attacks to happen. And conspiracy theories started to flourish on the new social media sites: Facebook. Youtube. Twitter. The facts have not been verified.

Tea Party members argued that a globalist conspiracy caused the economic downturn. In 2012, Donald Trump tweeted “an extremely credible source … told me @BarackObama’s birth certificate is a fraud.” In 2015, Trump was a presidential candidate.

And so it continues. Welsh logic and Welsh rhetoric have taken over much of the right with false myths tempting the weak mind. More than two-thirds of Republicans still don’t believe Joe Biden won the 2020 election. The QAnon conspiracy theory – which argues that Democrats in the so-called deep state undermined Trump to cover up their child sex racket – has at least one member of the Congress.

Millions of Americans will not take vaccines to prevent COVID-19 because they don’t trust the science.

Today we are all stuck in the roller coaster of Robert Welch’s political imagination, and we can’t take it anymore.

Edward H. Miller is Associate Professor at Northeastern University and author of the forthcoming book A Life of Conspiracy: Robert Welch, the John Birch Society, and the Revolution of American Conservatism.

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Mustang Bio announces targeted CAR T data for the MB-106 CD20 https://vetclinpathjournal.org/mustang-bio-announces-targeted-car-t-data-for-the-mb-106-cd20/ Fri, 07 Jan 2022 19:05:00 +0000 https://vetclinpathjournal.org/mustang-bio-announces-targeted-car-t-data-for-the-mb-106-cd20/

WORCESTER, Mass., Jan. 7, 2022 (GLOBE NEWSWIRE) – Mustang Bio, Inc. (“Mustang”) (NASDAQ: MBIO), a clinical-stage biopharmaceutical company focused on translating today’s medical breakthroughs into therapies cells and genes in potential cures for hematologic cancers, solid tumors and rare genetic diseases, today announced that interim phase 1/2 data on MB-106, an autologous CAR T cell therapy targeted against CD20 for patients with relapsed or refractory non-Hodgkin’s B-cell lymphoma (“NHL”) and chronic lymphocytic leukemia (“CLL”), were selected for poster presentation at the 2022 Tandem Meetings I Transplantation & Cellular Therapy Meetings ‘American Society of Transplantation and Cellular Therapy (“ASTCT”) and the Center for International Blood & Marrow Transplant Research (“CIBMTR”), which will take place February 2-6, 2022 in Salt Lake City, Uta h (“2022 Tandem Meetings”). MB-106 is being developed as part of a collaboration between Mustang and the Fred Hutchinson Cancer Research Center (“Fred Hutch”).

Manuel Litchman, MD, President and CEO of Mustang, said, “The compelling clinical activity and favorable safety profile that MB-106 continues to demonstrate in the ongoing Phase 1/2 trial in Fred Hutch demonstrate its potential as an outpatient treatment for patients with relapsed or refractory non-Hodgkin’s B-cell lymphoma and chronic lymphocytic leukemia. We look forward to the updated data that will be presented by Fred Hutch at the 2022 Tandem Meetings, particularly for patients with diffuse large B-cell lymphoma and Waldenstrom’s macroglobulinemia. We also look forward to advancing our targeted CAR T cell therapy program MB-106 CD20 to a multi-center trial as part of the IND of Mustang during the current quarter.

The details of the presentation are as follows:

Title: High efficacy and low toxicity of MB-106, a third generation CD20 targeted CAR-T for the treatment of B-NHL and relapsed / refractory CLL
Poster Number: 225
Dates and times: Thursday February 3 from 6:45 p.m. to 8:15 p.m. and Saturday February 5 from 6:15 to 7:45 p.m.
Presenter: Mazyar Shadman, MD, MPH, associate professor, clinical research division, Fred Hutch, Seattle, WA; Physician at Seattle Cancer Care Alliance; Associate Professor, Division of Medical Oncology, University of Washington School of Medicine

For more information, please visit the Tandem Meetings 2022 website at https://na.eventscloud.com/ehome/644055/1151300/.

Note: Fred Hutch scientists played a role in the development of these discoveries, and Fred Hutch and some of his scientists may benefit financially from this work in the future.

About MB-106 (CD20 Targeted CAR T Cell Therapy)
CD20 is a membrane-integrated surface molecule that plays a role in the differentiation of B cells into plasma cells. The CAR T was developed by Mustang research collaborator Fred Hutch in the labs of the late Oliver Press, MD, Ph.D., and Brian Till, MD, associate professor in the clinical research division of Fred Hutch, and licensed exclusively from Mustang in 2017. The lentiviral vector drug substance used to transduce patient cells to create the MB-106 drug product produced at Fred Hutch has been optimized as a third generation CAR derived from fully antibody. human, and MB-106 is currently in a phase 1/2 open-label dose escalation trial in Fred Hutch in patients with B-NHL and CLL. The same lentiviral vector drug produced at Fred Hutch will be used to transduce patient cells to create the MB-106 drug product produced at Mustang Bio’s cell processing facility in Worcester, MA, for administration as part of the multicenter phase 1/2 clinical trial slated to be launched shortly as part of Mustang Bio’s IND. It should be noted that Mustang Bio made minor improvements to its cell treatment to facilitate a possible commercial launch of the product. In addition, prior to commercial launch, Mustang Bio will replace the lentiviral carrier drug substance Fred Hutch with a carrier produced by a commercial manufacturer. Additional information about the trial is available at http://www.clinicaltrials.gov using the identifier NCT03277729.

About Mustang Bio
Mustang Bio, Inc. is a clinical-stage biopharmaceutical company focused on translating today’s medical breakthroughs in cell and gene therapy into potential cures for hematologic cancers, solid tumors and rare genetic diseases. Mustang aims to acquire rights to these technologies by licensing or acquiring an interest, to fund research and development, and to license or bring the technologies to market. Mustang has partnered with leading medical institutions to advance the development of CAR-T therapies for multiple cancers, as well as lentiviral gene therapies for severe combined immune deficiency. Mustang is registered under the Securities Exchange Act of 1934, as amended, and files periodic reports with the United States Securities and Exchange Commission (“SEC”). Mustang was founded by Fortress Biotech, Inc. (NASDAQ: FBIO). For more information, visit www.mustangbio.com.

Forward-looking statements
This press release may contain “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, each as amended. Such statements include, without limitation, any statement relating to our growth strategy and product development programs and any other statements which are not historical facts. Forward-looking statements are based on management’s current expectations and are subject to risks and uncertainties that could adversely affect our business, results of operations, financial condition and the value of our shares. Factors that could cause actual results to differ materially from those currently anticipated include: risks related to our growth strategy; our ability to secure, execute and maintain funding and strategic agreements and relationships; risks linked to the results of research and development activities; risks associated with the timing of the start and end of clinical trials; uncertainties related to preclinical and clinical trials; our dependence on third party suppliers; our ability to attract, integrate and retain key personnel; the initial stage of products under development; our need for substantial additional funds; government regulations; patent and intellectual property issues; competetion; as well as other risks described in our filings with the SEC. We expressly disclaim any obligation or commitment to publicly release any update or revision to any forward-looking statement contained herein to reflect any change in our expectations or any change in the events, conditions or circumstances upon which such statement is based, except as required by law, and we claim safe harbor protection for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995.

Company details :
Jaclyn Jaffe and Bill Begien
Mustang Bio, Inc.
(781) 652-4500
ir@mustangbio.com

Investor Relations Contact:
Daniel Ferry
LifeSci Advisors, LLC
(617) 430-7576
daniel@lifesciadvisors.com

Media Relations Contact Person:
Tony plohoros
6 degrees
(908) 591-2839
tplohoros@6degreespr.com

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What should a principled conservative do about Trump? (with Mona Charen) https://vetclinpathjournal.org/what-should-a-principled-conservative-do-about-trump-with-mona-charen/ Wed, 05 Jan 2022 15:40:28 +0000 https://vetclinpathjournal.org/what-should-a-principled-conservative-do-about-trump-with-mona-charen/

For decades, Mona Charen has been one of the foremost right-wing political writers and commentators. A speechwriter for Republican luminaries such as Nancy Reagan and Jack Kemp, she has worked at the Reagan White House and has been writing a national column since 1987. Believes Donald Trump has “totally discredited” conservatism. She is now editor-in-chief of The Bulwark (one of the leaders of the Never-Trump right) and host of the Beg to Differ podcast.

Mona Charen has long been critical of leftist dogma, particularly what she sees as an attack by modern feminism on the family and other key supporters of American society. But she was also one of the contributors to the National Review’s “Against Trump” symposium in January 2016, noting that Trump “represents all the stereotypes the left has put forward about what conservatism really is.” Unlike almost every other contributor to this question, she has consistently criticized Trump – and the hypocrisy her former Conservative comrades have shown towards Trump and other bad right-wing actors.

Today, Mona Charen remains critical of the left but believes that Trump and his movement pose a greater existential threat to American democracy. She has evolved into moderation and has demonstrated a commitment to civic dialogue and civil disagreement in her writing and podcasts. Join us to discuss his career and his efforts to articulate realistic, reasonable and responsible conservatism.

Transcription

Transcription to come 1/12/2022.

Photo credit: iStock

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How Racism Early in Life Can Affect Long-Term Health https://vetclinpathjournal.org/how-racism-early-in-life-can-affect-long-term-health/ Mon, 03 Jan 2022 17:00:33 +0000 https://vetclinpathjournal.org/how-racism-early-in-life-can-affect-long-term-health/

The scientific evidence is crystal clear: Early experiences literally shape the architecture of the developing brain. This widespread understanding is leading to increased public support for universal kindergarten to improve school readiness for all children and level the playing field for children facing adversity. But here is something less known to the general public: With the brain connected to the rest of the body, the first experiences affect all of our biological systems, for better or for worse, starting in utero and all the crucial years that follow.

This larger message sends an important wake-up call: We all need to start paying more attention to the science that explains how excessive adversity can harm lifelong health as well as early learning. . This knowledge can help us better understand why people of color in the United States are at higher risk for developing chronic diseases and aging prematurely than white people.

With growing evidence for the early origins of disparities in physical and mental health, focusing solely on brain development and learning only confronts one dimension of the pervasive racism-related inequalities that plague American society. Case in point: Although the educational achievement gap between black and white children has narrowed from 30% to 40% since the 1970s, reducing racial disparities in health has been more difficult. For example, premature births and low birth weight, which are associated with an increased risk of cardiovascular disease and subsequent diabetes, occur at a rate about 1.5 to 1.6 times greater in non-Hispanic blacks than among non-Hispanic whites, and these gaps persisted for decades.

A growing body of scientific evidence tells us that the foundations for lifelong health are built during the prenatal period and early childhood. Factors that promote positive outcomes include supportive relationships, safe physical environments, and sufficient resources to meet basic needs such as food and shelter. Take any of these protective factors away or add the weight of undue hardship or threat outside the family, and you tip the scales toward a greater risk of future problems.

Despite the critical influence of these early years, long-term results are neither inevitable nor biologically predetermined. Of course, physical and mental health is influenced by our genetics, but the chances of problems actually developing are strongly influenced by the environments in which we live. Policies, conditions and resources that address inequalities and ensure conditions conducive to healthy young children, as early as possible, will help build a healthier society. In other words, it is racism, not race, that is at the root of the persistent disparities in physical and mental well-being.

Race is a social invention. All humans, regardless of their skin color, share 99.9% of the same genome. Residential segregation – one of the many converging consequences of systemic racism, personal discrimination and poverty – leads to significant inequalities in exposure to air pollution, other environmental toxins and violence neighborhood, as well as unequal access to nutritious food, stable housing, and education and health care. The differences between blacks and whites in preterm births have been well documented and linked to the stress associated with discrimination, regardless of socioeconomic status. Black children are three times more likely than white children to lose their mothers before the age of 10.

How can the impacts of adversity from racism in early childhood affect the health of a lifetime? One answer lies in the particular sensitivity of young and developing bodies to the physiological effects of a stressful environment. We all know what stress looks like physically, and science explains the source of these sensations.

When faced with an acute challenge or threat, the stress response systems inside our bodies activate. Blood pressure and heart rate increase. Stress hormones such as cortisol are elevated. The immune system triggers an inflammatory response to prepare for wound healing and fight infections. Metabolic systems mobilize blood sugar to fuel the “fight or flight” response. Once the threat is managed, the stress response (which can save lives) returns to baseline. But if the level of adversity remains high for long periods of time (from chronic discrimination or poverty, for example), the continued activation of the stress response can have a wear and tear effect on the inside of the body that leads to “toxic stress” and a host of health problems.

For example, excessive inflammation can affect multiple organ systems and increase the likelihood of developing heart disease and autoimmune disorders. Prolonged elevations in blood sugar can lead to insulin resistance, obesity, metabolic syndrome, and diabetes. Once we understand the biology of adversity and resilience, we can see how the excessive activation of stress early in life does not lead to inevitable illness but increases the risk of later problems, many of which include the pre-existing medical conditions associated with more serious illness from Covid19. The high prevalence of these conditions among people of color may thus explain part of the marked racial / ethnic differences in hospitalization and death rates from the pandemic.

Much of the public debate on disparities in health outcomes focuses on unequal access to medical care, unequal treatment in the health system, and the impacts of lifestyles and individual responsibility on health. adulthood. But science tells us that preventing or lessening the effects of adverse experiences and exposures in infancy could be as important to long-term health as the conditions we live in as adults and the medical care we receive. .

A better understanding of how the synergistic tensions of systemic racism, interpersonal discrimination and intergenerational poverty can be integrated into the body can be a powerful tool on the road to a healthier and more just world. Science tells us that the road must begin in the first years of life.

10.1146 / knowable-121121-1

This article originally appeared in Known magazine, an independent journalistic company of Annual Reviews. Register to receive the newsletter.

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The art of being a happy pessimist https://vetclinpathjournal.org/the-art-of-being-a-happy-pessimist/ Sat, 01 Jan 2022 19:30:11 +0000 https://vetclinpathjournal.org/the-art-of-being-a-happy-pessimist/

There is a cult of “positivity” that rules the world. Through countless self-help books, banal social media slogans, and WhatsApp hello messages, this cult will have you believing “Think Positive” is the magic pill for mental health. Pop one to instantly make that glass half empty half full and all around you bright and sunny.

But isn’t it painful to seem continually optimistic even when you’re anxious and bogged down? And what about those of us who naturally take a more cautious view of the world? When things are very clearly not going well, can we really activate that “be optimistic” button and feel good?

Turns out, practically, physiologically, and psychologically, pessimism isn’t always the bad guy popular culture claims to be. And, in more than one way, certain forms of pessimism can also work to our advantage.

The case of constructive pessimism

First of all, a positive attitude is great. We all love the happy people around us. The melancholics are short. And our lived experience tells us that life is easier when you are hopeful and jovial. Additionally, there is a lot of research suggesting that optimism has many health benefits. Studies have shown that optimistic people are less prone to heart disease, strokes and cancer. So it’s no wonder that there is relentless social pressure on us to be eternal optimists. This is where the problem lies.

Experts believe our moods and views are part of an optimism-pessimism spectrum. On opposite ends of this spectrum are the pure optimists, who can be detached from reality, and the pure pessimists, who can be unhappy, according to Dr. Elizabeth Scott, award-winning author and blogger on stress management and wellness. emotional.

While purists are a small minority, the majority of us fall somewhere in the middle of the spectrum. And while, generally, most of us are optimistic about some areas of our lives and not others, our natural state of being leans towards one of the two ends of the spectrum, writes Dr Scott in a medically revised article.

So, in the words of Dr Alok V Kulkarni, a senior consultant psychiatrist at a Hubli-based mental health institute, “optimism, while desirable, is not the default state of mind for everyone.” . It depends on various factors – birth traits, stable upbringing, positive life events, sense of security, and positive feelings about self-esteem, self-image, self-esteem and self-identity – says Dr Kulkarni. So, it follows that the majority of people are either generally optimistic or generally pessimistic due to their birth traits and the type of life they have had from infancy through adolescence and youth.

Most importantly, “it is not possible to fundamentally change a person,” says Dr Raghu K, chief psychiatrist at a multi-specialty hospital based in Bengaluru. According to him, there is a socio-cultural dimension in the way we think about optimism and pessimism. “Nothing is waste in nature,” he says. If a particular trait exists, then it has its uses in our life and survival. But how we view or rank the trait – positive or negative, good or bad – is only a social construct. Simply put, the company has its own way of creating a narrative. If he views a particular trait favorably, then anyone who exhibits that trait is referred to as a positive personality, and vice versa.

Against the backdrop of pessimism, we know this has been a useful trait throughout our evolution, because being nervous, anxious, and worried about things that might go wrong has kept us alive. But most modern societies, including our own, view pessimism as a negative emotion. And so those of us who are not naturally optimists are desperate to deny and stifle our pessimistic instincts, even though the struggle to become optimistic is sometimes more painful than being a pessimist.

The irony here is that the tendency to force positivity and resist negativity can actually hurt the truly anxious. Psychologist and writer Dr. Douglas LaBier says mental health and well-being comes from embracing “bad feelings” and not pushing them away. He says that while meditation, yoga, and other mind-body practices can help us deal with negativity, the process must begin with accepting our so-called negative emotions.
So, to sum it up in Dr. Raghu’s words, “if you are born with a particular trait, you must embrace it and regard it as your strength”. And this also applies to pessimism.

How to accept pessimism

That’s not to say that we should all proactively develop a more pessimistic outlook on life. But if we are naturally inclined to have a pessimistic view, how can we use this trait as a strength?

Some of the benefits of having a pessimistic outlook are intrinsic to the way these personalities think and behave. More often than not, they expect negative results and are pleasantly surprised when things go well. So it’s no surprise that a 2013 study published in the Journal of Research in Personality shows that people with negative outlooks are better than their more optimistic peers when it comes to building safety nets, to prepare (practically and emotionally) for bad situations, and hold on to their worldview in crises. We can also assume that since pessimists focus on detecting obstacles in their path, they are better able to assess risks and avoid them.

Research indicates that a pessimist’s chronic tendency to have negative expectations (dispositional pessimism in psychologist parlance) can also be a big advantage, especially in the relationship arena.

A study published in the Journal of Personality and Social Psychology concludes that sometimes too much optimism can be a handicap in a marriage or relationship because it prevents couples from proactively engaging in problem solving. Conversely, couples who take a more cautious approach to their relationship tend to experience more long-term success and satisfaction, as they start out with lower expectations about each other’s ability to cope and, therefore, to make more efforts.

There is also a way to use pessimism as a strategy for dealing with anxiety and dealing with difficult real life situations. Psychologists call this “defensive pessimism,” and it is based on the fact that people with negative outlooks tend to imagine worst-case scenarios over and over and become anxious. However, practitioners of defensive pessimism exploit this trait to perform better than they would by thinking positively.

When a defensive pessimist begins to feel anxious about an event or situation, they first drastically lower their expectations, and then think vividly and specifically about all the things that could go wrong. In the process, she is able to create a plan of action to deal with any potential setbacks. To better understand, think about an upcoming public speaking event that is making you nervous. Using the principles of defensive pessimism, start by telling yourself it’s going to be a disaster. Then imagine in detail all the worst-case scenarios: you forget a key data point, you stumble on the microphone wire, etc.

Seeing this disaster unfold in your mind, you prepare to take concrete mitigating action – carry a landmark card with the data point, ask the organizers for a wireless microphone, and more. Thus, you feel more in control and therefore less anxious.

Best of all, of course, you are now very well prepared, better prepared than you would be if you thought the event would go well.

Does Pessimism Really Affect Your Health? Ask the Japanese

Everyone and their aunt believe that optimists are healthier than pessimists. The reality is, for every study that claims the health benefits of optimism, there is one that shows the longer life expectancies of pessimists. Finnish study links pessimism to heart disease, but UK study finds no link between positivity and longevity. Thus, contrary to popular perception, the scientific evidence to support the health benefits of optimism or the detrimental effects of pessimism is inconclusive, contradictory and controversial.

A 2017 study comparing the adult populations of America and Japan is a good reference in this context. Entitled “Linking Positive Affect to Blood Lipids: A Cultural Perspective,” the study found that Americans were more likely to have healthier cholesterol levels and less likely to be overweight if they were optimistic. But no such connection could be found for the Japanese. In East Asian cultures, such as Japan, positive emotions are not viewed favorably and are seen as a distraction. But paradoxically, the Japanese are known to lead long and healthy lives. So, if pessimism is unhealthy, what explains the Japanese paradox?

It is impossible to find the exact cause and effect in studies like this. But look at it with a socio-cultural lens and the answer seems clear. In American society optimism is a strongly reinforced value while in Japan the cultural emphasis is on living with a cautious attitude. So, it may not be optimism or pessimism, but our ability to live in tune with the dominant culture that makes us healthy or unhealthy.

The worst is yet to come?

You can trust the Swedes to be the first to greet anything to the contrary. This is also true for the happy pessimism which is gaining a lot of space in Sweden. Battling the pressure to relentlessly be seen as positive, many Swedes encourage a growing cult that promotes healthy negative thinking. In fact, a course titled “Negative Thinking: It Won’t Get Any Better Than This” by practical philosopher and psychologist Ida Hallgren ran out of applications in a day.

Psychologist and comedian Mattias Lundberg, who has co-authored a book on happy pessimism, writes that there’s no denying the power of optimism, but the self-help industry has “twisted the term.”

“Unlimited positivity has in a way become a necessary condition for happiness. And in this hypothesis could lie a great danger”, he would have declared in an article published in a large Swedish newspaper.

Hallgren’s course, by the way, is built around three phases of pessimism. It begins with the Greek Stoics, continues through to 19th century pessimism “guru” Arthur Schopenhauer and ends with Buddhism. Hallgren explains that the negative thinking movement is about recognizing reality, “even the ugliest of things,” not expecting the worst in life.

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Second mural from the Historical Society to represent the Amerindians from 2,000 to 4,000 years ago https://vetclinpathjournal.org/second-mural-from-the-historical-society-to-represent-the-amerindians-from-2000-to-4000-years-ago/ Fri, 31 Dec 2021 03:05:45 +0000 https://vetclinpathjournal.org/second-mural-from-the-historical-society-to-represent-the-amerindians-from-2000-to-4000-years-ago/

Heading into 2022, professional artist David Boatwright is expected to start work on the second mural project funded and supervised by the Bulloch County Historical Society to fill a highly visible wall in downtown Statesboro.

It was Boatwright and fellow artist Michael Kuffel, both from Charleston, South Carolina, who in early 2020 painted “The Fabulous Fifty of 1906” on the wall at 48 East Main Street facing the side. drive from Statesboro City Hall. This mural depicts December 2, 1906, the return by train of the delegation that secured the district’s first agricultural and mechanical school for Statesboro, which grew through other identities to become the University of Southern Georgia.

For its second mural project, the Historical Society worked with the university’s sociology and anthropology department to delve much deeper into the past of what is now Bulloch County, explained the executive director of the company, Virginia Anne Franklin Waters. The planned set of five paintings on the west-facing wall of the Averitt Center for the Arts at 41 West Main St., the side that includes the entrance to the Whitaker Black Box Theater, will represent Native Americans of the Archaic period. late, from 2,000 to 4,000 years ago.

This mock-up of one of five murals planned for 41 W. Main St. shows Native Americans of the Late Archaic period, 2,000 to 4,000 years ago, emptying baskets onto a pile of mussel shells. pure water.

“I think we’re all very happy with our first mural in downtown Statesboro, and we wanted the second to be in downtown Statesboro, for obvious reasons,” Waters told Statesboro City Council. “That first mural was about something that changed all of our lives, and it was getting to college and then university here, but I think one area of ​​our history that has been seriously neglected is the locals. origin of this region, and we are tackling this. “

Before the Mississippians

The people of the Archaic period were not the same as the last Native Americans of the Mississippian culture who built structures such as the Ocmulgee mounds in Macon and were the ancestors of the Muscogee, or Creek tribes. But according to research carried out by the Department of Sociology and Anthropology over the past three years, the Archaic period, during which indigenous peoples made and used spears but not yet bows and arrows, would have been one of the most active periods in prehistoric times. from that part of Georgia, she said.

Waters presented the mayor and council with five illustrations depicting the wall panels, but which she said were not the Boatwright originals, but ‘Photoshopped’ concept images. It will be guided by more specific information received directly by working with researchers at Georgia Southern, Waters said.

Mural 1.jpg

This conceptual image from one of five paintings for the wall at 41 West Main Street depicts Native Americans from the Late Archaic period 2,000 to 4,000 years ago fishing for fish with a dam made of wooden moats .

Life by the rivers

One of the conceptual images shows people from the Archaic Period fishing for fish using baskets and a weir, or fish trap, made up of a moat inserted into the bed of a river to form a partially circular enclosure with an upstream opening. Another of the images shows individuals emptying baskets onto a heap, or heap of debris, made up mostly of freshwater mussel shells, which was another important food source. In the background of this image are people doing other tasks, such as cooking over a fire in front of hut-shaped houses. Other images show dugout canoes being made and perch along a blackwater stream and another view of village activities.

The exterior wall of 41 West Main on which the murals are to be painted has several raised vertical elements in the form of columns, dividing it into segments. Five of the wall segments contain small windows and the murals will be painted below the windows, Waters said in an interview.

City variation

Due to the size of the wall plan, an exemption from city law was required. In fact, a current Statesboro ordinance limits murals to only 25% of a single building facade. But city staff members recommended approval of the waiver with one condition, that the final specifications be reviewed and approved by city staff. The city’s planning commission by a 5-0 vote on December 7 recommended approval, and city council, by a 4-0 vote, approved the exemption on December 21.

“This project is blessed by Georgia and the National Council on Native American Relations,” Waters told the mayor and council of Statesboro. “It’s big. So when we get our dedication, there will be people coming from Washington because we broke new ground on this archaic group here. “

She noted that the Bulloch County Historical Society had already spent $ 3,200 to cover the wall with a base coat of paint, suitable for containing murals, in a shade called camel hair. To paint the mural, the company pays Boatwright $ 25,000 – Waters said this was a base price, so the final cost would be at least equal to that – and he would have to complete the work in about six weeks.

Boatwright is expected to arrive in town on Sunday and begin work on Monday, Jan.3, Waters said. She has a friend who hosts the artist (s) for free.

After the mural is completed, a large bronze plaque made by the International Bronze Company will be affixed to the building, along with text providing information about the area’s Archaic period residents, Waters said.

It is therefore a global project of approximately $ 30,000. The Historical Society’s primary source of funding for all of its projects is the Jack N. and Addie D. Averitt Foundation. With nearly 400 members now, the society also collects between $ 30,000 and $ 40,000 per year in dues.

Averitt Center website

In addition to collaboration with researchers at Georgia Southern University, the project of course involves cooperation with the Averitt Center for the Arts. Current Averitt Center Board Chair Kelly Berry served on the Bulloch County Historical Society Board of Trustees, and Waters now sits on the Averitt Center Board of Trustees.

In a phone interview, Averitt Center executive director Rahn Hutcheson said the basecoat had already improved the wall and he was eager to see what Boatwright would add.

“He did such a fantastic job on this 1906 mural that we’re looking for something really, really interesting and cool on this site,” Hutcheson said. “You know, this area has just been dormant and vacant for so long, and I think it’s gonna be pretty cool. “

He noted that the wall is visible from the Statesboro post office, as well as drivers coming from the west and south.

“It’s a wonderful, wonderful place for something that’s educational, and I know that’s what the Historical Society is trying to do,” Hutcheson said.

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Million-pound artwork, once doomed for demolition, finds a new home https://vetclinpathjournal.org/million-pound-artwork-once-doomed-for-demolition-finds-a-new-home/ Wed, 29 Dec 2021 14:40:00 +0000 https://vetclinpathjournal.org/million-pound-artwork-once-doomed-for-demolition-finds-a-new-home/

A million-pound art installation in Washington, DC, once marked for demolition, will be relocated instead, thanks to a new agreement between the National Geographic Society and American University.

National Geographic executive staff declined to be interviewed, but released a statement saying they were “happy” with plans to move Elyn Zimmerman’s iconic stone and water facility “Marabar” from its grounds at the university campus. The deal ends a debacle that began almost three years ago, when the company told Zimmerman it no longer wanted his sculptural work, erected in 1984.

“It is a piece that is part of the history of landscape architecture,” said Jack Rasmussen, director of the American University Museum, which will now be responsible for safeguarding “Marabar”. “A woman sculptor in the 1970s and 1980s who did that?” It’s revolutionary.

Members of the company’s board of directors had applauded when the plans for “Marabar” were unveiled, according to David Childs, the architect who selected Zimmerman to create the installation, a few blocks north of the House. White. Zimmerman, 76, named his work, a grouping of granite stones around a pool of bubbling water, after the fictional caves in EM Forster’s novel, “A Passage to India”.